Fertility Sparing UFE
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Fertility-Sparing Fibroid Embolization (Partial UFE)

Treat fibroids
without surgery — and protect your fertility.

Partial uterine fibroid embolization is a minimally invasive, image-guided procedure that blocks only the small vessels feeding your fibroids, while leaving the larger vessels and surrounding healthy uterine tissue with their blood supply. No incision, no general anesthesia, no hospital stay. Performed as an outpatient by Dr. Atabak Allaei, a double board-certified interventional radiologist.

Saves your uterus
Outpatient · no hospital stay
Treats all fibroids at once
Minimally Invasive · Outpatient

Fertility-sparing UFE at a glance

A non-surgical, image-guided procedure — recovery in days, not weeks.

40%

Spontaneous pregnancy within 2 years in a 359-woman study

All

Fibroids treated at once — uterus preserved

Days

Recovery — versus weeks for surgery

10,000+

Image-guided procedures, incl. 2,000+ embolizations

Quick Answer

Fertility-sparing (partial) uterine fibroid embolization treats fibroids by blocking only the small arteries that feed them, leaving the larger vessels open. Through a small nick in the wrist or groin, Dr. Allaei delivers tiny particles under X-ray guidance, so the fibroids shrink while healthy uterine tissue keeps its blood supply. There is no incision, no general anesthesia and no hospital stay, and pregnancy after the procedure has been well documented.

No surgery

Small nick in the skin

Saves your uterus

Unlike hysterectomy

All fibroids

Treated at once

Fast recovery

Days, not weeks

In brief

Key takeaways: fertility-sparing UFE

  • Targeted, not total: Only the small vessels feeding the fibroids are embolized, leaving larger vessels and healthy uterine tissue with their blood supply.
  • Non-surgical and outpatient: A small nick in the skin, no general anesthesia, no stitches and no hospital stay.
  • Pregnancy is possible: In a study of 359 women unable to conceive, 40% became pregnant spontaneously within two years of UFE.
  • Compare honestly: See how pregnancy rates after UFE and after myomectomy compare in head-to-head studies, below.
  • Treats all fibroids at once and saves your uterus — unlike myomectomy or hysterectomy.
  • Shared decision-making: Your fertility goals, health and preferences guide whether partial UFE is the right choice.

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Understanding the condition

What are uterine fibroids?

Uterine fibroids are non-cancerous growths in the uterus — a common gynecological condition affecting many women of reproductive age.

Bleeding
Heavy menstrual bleeding

Prolonged or heavy periods are one of the most common fibroid symptoms.

Pain
Pelvic pain and pressure

Fibroids can cause pelvic pain, pressure and an enlarged uterus.

Fertility
Difficulty conceiving

Fibroids can interfere with conception and pregnancy.

Uterine artery embolization (UAE), also called uterine fibroid embolization (UFE), has been an effective, minimally invasive treatment for fibroid symptoms for over 20 years. For women who want to become pregnant, however, a key question has been how treatment affects future fertility.

Partial uterine fibroid embolization was developed to answer that concern. It aims to strike a balance between relieving symptoms and preserving fertility — making it a promising option for women who want to protect their ability to conceive.

The difference

Traditional vs. partial uterine fibroid embolization

Both block blood flow to fibroids. Partial UFE is more targeted — embolizing only the small vessels to the fibroids and leaving the larger vessels open.

Conventional
Traditional UAE
  • Small particles are injected into the uterine arteries
  • Blood flow to the fibroids is blocked, so they shrink
  • Highly effective for symptom relief
  • Concerns about its effect on fertility led to a more refined approach
Fertility-sparing · what we offer
Partial UFE
  • Only the small arterial vessels to the fibroids are embolized
  • The larger vessels of the fibroids are left open
  • Surrounding healthy uterine tissue keeps its blood supply
  • Designed to limit injury to the uterus and nearby reproductive organs
Uterine Artery Embolization
UFE can be performed through the wrist (radial) or groin.
ufe fibroid embolization radial access arm specialist doctor california
Particles block the small vessels feeding the fibroids.
Compare your options

Fibroid embolization vs. surgery

Compared with myomectomy and hysterectomy, embolization needs no incision, no general anesthesia and no hospital stay — and it treats all fibroids at once while saving your uterus.

FactorPartial UFEConventional UFEMyomectomyHysterectomy
IncisionSmall nick in the skinSmall nick in the skinSurgical incisionSurgical incision
AnesthesiaNo general anesthesiaNo general anesthesiaGeneralGeneral
Hospital stayNone — outpatientNone — outpatientOften requiredRequired
Uterus preservedYesYesYesNo — uterus removed
Treats all fibroids at onceYesYesNot alwaysYes (uterus removed)
RecoveryA few daysA few daysA few weeksA few weeks
Blood lossVirtually noneVirtually nonePossible transfusionPossible transfusion
Future pregnancyPossible; designed to protect fertilityPossiblePossible; traditionally recommended when pregnancy is the main goalNot possible

Advantages of fibroid embolization over surgery

  • No stitches
  • No major scar or surgical incision — only a small nick in the skin
  • No general anesthesia required
  • No burning or scraping the lining of the uterus
  • No internal cutting, bleeding or scarring
  • No risks of hysterectomy
  • No hospital stay — outpatient procedure
  • Treats all fibroids at once (unlike myomectomy)
  • Saves your uterus (unlike hysterectomy)
  • Fast recovery — a few days versus a few weeks for surgery
  • Low risk of complications
  • Virtually no blood loss (versus possible transfusions)
  • Significant improvement in quality of life
  • Successful for over 20 years

These are just a few of the benefits over surgery. Read more about the advantages of UFE or see our full treatment comparison chart.

Fertility

How partial UFE is designed to protect fertility

By embolizing only part of the fibroid’s blood supply, partial UFE aims to relieve symptoms while keeping the uterus as healthy as possible for a future pregnancy.

Preserves uterine tissue

Selective embolization limits damage to the surrounding uterine tissue — important for women hoping to conceive, since the health of the uterus matters for a successful pregnancy.

Maintains blood flow

Leaving the larger vessels open keeps blood flowing to the rest of the uterus and surrounding tissues, supporting overall uterine health.

No surgical scarring

There is no internal cutting of the uterus, so there is no surgical scar on the uterine wall.

Step by step

How is fertility-sparing UFE performed?

An outpatient procedure under local anesthesia through a small nick in the skin — no incision, no stitches and no hospital stay.

1

Numbing & access

A local anesthetic numbs the skin, and a tiny tube is placed in an artery in the wrist (radial) or groin.

2

Map the uterine arteries

Live X-ray imaging guides the catheter into the uterine arteries and shows the vessels feeding each fibroid.

3

Partial embolization

Tiny particles are delivered to the small vessels supplying the fibroids, deliberately leaving the larger vessels open.

4

Go home & recover

No hospital stay. Most women recover in a few days, versus a few weeks after surgery.

Research evidence

Pregnancy after UFE vs. myomectomy: what the research shows

Head-to-head studies show mixed results. One randomized trial favored myomectomy, another favored embolization, and a 2024 meta-analysis found comparable pregnancy rates.

StudyAfter UFEAfter myomectomyWhat it measured
Mara et al., 2008
Randomized trial · 121 women planning pregnancy, fibroids larger than 4 cm
50%78%Pregnancy rate among women who tried to conceive in the first 2 years.
FEMME trial, 2020
Randomized trial · 254 women (New England Journal of Medicine)
8%4%Pregnancy within 2 years. Most participants were not trying to conceive, so rates are low in both groups.
Meta-analysis, 2024
13 studies, including 4 randomized trials
ComparableComparableBoth procedures showed comparable improvement in pregnancy rates.
Pisco et al., 2017 — partial UFE
359 women unable to conceive · no myomectomy comparison group
40.1%Not studiedSpontaneous pregnancy within 2 years; 36.7% probability of pregnancy with a live birth.

What this means for you. Myomectomy has traditionally been recommended when pregnancy is the main goal, and a Cochrane review found low-quality evidence that it may offer better fertility outcomes than conventional UFE. However, the randomized trials were small and their results conflict, and neither one studied partial UFE.

Partial UFE was developed specifically for women who want to conceive, and pregnancy after it is well documented — including in women who could not conceive before treatment. The right choice depends on your age, the size, number and location of your fibroids, and your fertility goals. Dr. Allaei will review your case and talk through both options with you.
Understanding the numbers

Why don’t all women conceive after UFE or myomectomy?

Treating fibroids removes one possible barrier to pregnancy — but fertility depends on many other factors. That is why no fibroid treatment, surgical or non-surgical, reaches 100%.

Factors that affect any woman’s fertility

Age

Fertility naturally declines with age, especially after 35. Women treated for fibroids are often in their late 30s or 40s, which affects pregnancy rates after any treatment.

Egg supply (ovarian reserve)

The number and quality of eggs decrease over time. A simple blood test (AMH) can help estimate your egg supply before treatment.

Partner factors

Male-factor infertility contributes in many couples who have trouble conceiving, so a semen analysis is an important part of any fertility evaluation.

Fallopian tubes

Blocked or damaged tubes can prevent pregnancy regardless of how well the fibroids are treated. Learn about tubal blockage treatment.

Other conditions

Endometriosis, adenomyosis, ovulation disorders and thyroid problems can all affect fertility independently of fibroids.

Not everyone was trying

In some studies, many participants were not actively trying to conceive, or follow-up was too short to capture later pregnancies.

Treatment-related factors

Surgical

After myomectomy

  • Scar tissue (adhesions) can form inside or around the uterus and affect implantation or the tubes
  • A waiting period is usually advised so the uterine wall can heal before trying to conceive
  • Fibroids can grow back over time
  • When fibroids are numerous or deep in the uterine wall, not all may be removable
Non-surgical

After UFE

  • Changes to the uterine lining can occur — a hysteroscopy before trying to conceive can check for them
  • Fibroids shrink rather than disappear, so a large fibroid may still affect the uterine cavity
  • Rarely, reduced blood flow to the ovaries can affect egg supply, mainly in women closer to menopause
  • Partial UFE is designed to limit these effects by leaving the larger vessels and healthy tissue untouched

How we help improve your chances

  • We start with your fertility goals before recommending any treatment.
  • We suggest a fertility work-up first — such as an AMH test, a partner semen analysis and a tubal check — so other causes are not missed.
  • We use partial embolization to protect healthy uterine tissue.
  • We recommend a hysteroscopy before you start trying to conceive, when appropriate.
  • We coordinate with your gynecologist or fertility specialist so your care is planned together.
  • We tell you honestly when myomectomy may be the better option for you.
Is it right for you?

Partial UFE results and who is a candidate

Partial UFE is clinically successful in a large majority of patients, and pregnancy after treatment has been demonstrated — but individual characteristics must be considered.

Shared decision-making between you and an interventional radiologist trained in partial UFE is essential, so the treatment aligns with your fertility goals, overall health and preferences. Dr. Allaei reviews your imaging, labs and history to determine whether you are a candidate and the outcomes you can expect.

What is recovery like?

UFE is an outpatient procedure with no hospital stay. Most women recover in a few days, compared with a few weeks after surgery.

Is UFE covered by insurance?

UFE is covered by many insurance plans. Check if we’re in your network in under a minute.

Our patient experiences

Real results from our patients

Many of our patients were told surgery was their only option — and found a non-surgical alternative.

Find out if you're a candidate

Request an Appointment

Dr. Allaei will review your imaging, labs, history and fertility goals, and tell you whether fertility-sparing UFE is right for you.

  • Virtual video telehealth appointments available.
  • All appointments conducted by our board-certified doctor — not assistants or non-physician providers.

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Why California Fibroid Center

Not all embolizations are the same

Uterine artery embolization is offered by practitioners with varying levels of experience — and technique matters, especially when protecting fertility.

Uterine artery embolization (UAE), also called uterine fibroid embolization (UFE), has been an effective, minimally invasive treatment for fibroid symptoms for over 20 years. For women who want to become pregnant, however, a key question has been how treatment affects future fertility.

Our specialist performs a high number of embolizations — not only in the uterus but in higher-risk, complex organs such as the kidney, liver and lung. That breadth of experience allows complex fibroid and adenomyosis cases to be treated safely and effectively, and patients are often surprised how quick and simple their procedure was.

Embolization specialists

Our center and staff focus on embolization, from your first visit through recovery.

Complex-case experience

Embolizations in the kidney, liver, lung and other high-risk organs translate into precision in the uterus.

10,000+ procedures, 2,000+ embolizations

Extensive image-guided experience across the body.

Current techniques

Our specialist keeps up with the research to bring the newest technology and refines care based on patient feedback.

Experience you can trust

Who performs your fertility-sparing UFE?

Fertility-sparing UFE is performed by a Vascular & Interventional Radiologist trained in partial embolization — not a surgeon. At California Fibroid Center, every procedure is performed personally by Dr. Atabak Allaei, who has completed more than 10,000 image-guided procedures, including over 2,000 embolizations.

Dr. Atabak Allaei, double board-certified vascular and interventional radiologist and Medical Director of the California Fibroid Center

Atabak Allaei, MD

Double Board-Certified · Vascular & Interventional Radiology and Diagnostic Radiology

10,000+

Image-guided procedures

2,000+

Embolizations

  • Performs every procedure himself — not a physician assistant, nurse practitioner or rotating provider.
  • Reads your imaging himself. Board certification in Diagnostic Radiology means he plans your treatment from your own MRI or ultrasound images.
  • Complex embolization experience across the uterus, kidney, liver, lung and other high-risk organs — the precision partial UFE requires.
Double Board-Certified
Mallinckrodt Fellowship
10,000+ Procedures
2,000+ Embolizations
Physician-Performed

Why the specialty matters

Embolization is performed from inside the arteries through a small nick in the skin — the training and board certification of Vascular & Interventional Radiology. Gynecologists are trained in surgical treatments such as myomectomy and hysterectomy, which is why many women are never told a non-surgical option exists. Seeing both specialists before deciding can help you choose the right treatment.

Training and credentials

  • University of California, San DiegoBS, Biochemistry and Cell Biology — Summa Cum Laude
  • State University of New YorkDoctor of Medicine
  • Residency — New YorkRadiology
  • Mallinckrodt Institute of RadiologyFellowship in Vascular & Interventional Radiology — Washington University / Barnes-Jewish
  • Cedars-Sinai Medical Center & UCI HealthAttending physician; Medical Director, California Vascular & Interventional
Sources

References

  1. Pisco JM, Duarte M, Bilhim T, et al. Spontaneous pregnancy with a live birth after conventional and partial uterine fibroid embolization. Radiology. 2017;285(1):302-310. doi:10.1148/radiol.2017161495.
  2. Ghanaati H, Sanaati M, Shakiba M, et al. Pregnancy and its outcomes in patients after uterine fibroid embolization: a systematic review and meta-analysis. Cardiovascular and Interventional Radiology. 2020. doi:10.1007/s00270-020-02521-6.
  3. Mara M, Maskova J, Fucikova Z, Kuzel D, Belsan T, Sosna O. Midterm clinical and first reproductive results of a randomized controlled trial comparing uterine fibroid embolization and myomectomy. Cardiovascular and Interventional Radiology. 2008;31(1):73-85.
  4. Manyonda I, Belli AM, Lumsden MA, et al. Uterine-artery embolization or myomectomy for uterine fibroids. New England Journal of Medicine. 2020;383(5):440-451. doi:10.1056/NEJMoa1914735.
  5. Systematic review and meta-analysis of current evidence in uterine artery embolization vs myomectomy for symptomatic uterine fibroids. Scientific Reports. 2024. doi:10.1038/s41598-024-69754-0.
  6. Gupta JK, Sinha A, Lumsden MA, Hickey M. Uterine artery embolization for symptomatic uterine fibroids. Cochrane Database of Systematic Reviews. 2014;(12):CD005073. doi:10.1002/14651858.CD005073.pub4.

The above information explains what is involved and the possible risks. It is not meant to be a substitute for informed discussion between you and your doctor, but can act as a starting point for such a discussion.

Frequently asked questions

Fertility-sparing UFE: common questions

What is fertility-sparing (partial) uterine fibroid embolization?

Partial uterine fibroid embolization is a minimally invasive, image-guided procedure that treats fibroids by blocking only the small arterial vessels that feed them, while leaving the larger vessels open. This allows the surrounding healthy uterine tissue to keep its blood supply, with the goal of relieving symptoms while preserving fertility.

In traditional uterine artery embolization, particles are injected into the uterine arteries to cut off blood flow to the fibroids. In partial UFE, only the small vessels to the fibroids are embolized and the larger vessels are left patent, which is designed to limit injury to the uterus and nearby reproductive organs.

Yes, pregnancy after UFE has been well documented. In a study of 359 women with fibroids who were unable to conceive, the spontaneous pregnancy rate was 29.5% at one year and 40.1% at two years after UFE, and the probability of a pregnancy with a live birth at two years was 36.7%. Individual results depend on age, fibroid characteristics and other fertility factors.

Head-to-head studies show mixed results. In a randomized trial of 121 women planning pregnancy (Mara, 2008), 50% conceived after UFE compared with 78% after myomectomy. In the FEMME randomized trial of 254 women (NEJM, 2020), 8% reported a pregnancy within two years after UFE compared with 4% after myomectomy, although most participants were not trying to conceive. A 2024 meta-analysis of 13 studies found comparable improvement in pregnancy rates. Neither trial studied partial UFE. The right choice depends on your age, fibroids and fertility goals, and should be made together with your doctor.

Treating fibroids removes one possible barrier to pregnancy, but fertility depends on many other factors. The most important is age, since fertility declines especially after 35. Other factors include egg supply (ovarian reserve), male-factor infertility, blocked fallopian tubes, endometriosis, adenomyosis and ovulation disorders. Treatment-related factors can also play a role, such as scar tissue after myomectomy, or changes to the uterine lining after UFE. A fertility evaluation before treatment helps identify these issues.

Partial UFE is a minimally invasive procedure with no surgical incision, no general anesthesia, no hospital stay and virtually no blood loss. Like any procedure, it carries some risks, which Dr. Allaei reviews with you during your consultation.

Yes. Uterine fibroid embolization treats all fibroids at once, unlike myomectomy, which removes fibroids individually. It also saves the uterus, unlike hysterectomy.

No. UFE is performed as an outpatient procedure under local anesthesia through a small nick in the skin of the wrist or groin. There are no stitches and no hospital stay.

Most women recover in a few days, compared with a few weeks after fibroid surgery such as myomectomy or hysterectomy.

Fertility-sparing UFE is performed by a Vascular & Interventional Radiologist trained in partial embolization. At California Fibroid Center, Dr. Atabak Allaei, a double board-certified Vascular & Interventional Radiologist, performs every procedure personally.

UFE is covered by many insurance plans. California Fibroid Center offers an online insurance check so you can see whether we are in your network in under a minute.

Dr. Allaei has performed more than 10,000 image-guided procedures, including over 2,000 embolizations, in the uterus as well as complex organs such as the kidney, liver and lung.

Yes. Appointments are available by online video telehealth or in person at offices in Los Angeles, Orange County and San Diego.

Have more questions? See our full fibroid FAQ page.

Related fibroid treatments

Explore more image-guided treatments

Symptoms
Fibroids & Infertility
How fibroids affect fertility.
Fertility
Tubal Blockage Treatment
Non-surgical treatment for blocked tubes.
Condition
Adenomyosis
Embolization for adenomyosis.
Compare
Treatment Comparison Chart
UFE vs. myomectomy, hysterectomy and ablation.
About
Meet Dr. Allaei
The specialist who performs your procedure.

Don’t wait for your fibroids to get larger

Request an appointment to meet with our fibroid specialist, who will review your imaging, labs and history to determine if you are a candidate and the outcomes you can expect. Every woman is an individual and should discuss the risks and benefits of embolization and other treatments with our doctor. Telehealth and in-person visits available across Los Angeles, Orange County and San Diego.

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